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Understanding Novel Response Patterns of Immunotherapies

Immunotherapies display novel response patterns that affect the design of imaging based studies and the subsequent evaluation of imaging data. Applying traditional chemotherapy-based response assumptions to immunotherapy trials can result in inaccurate interpretation of response, premature therapy termination, and unnecessary removal of subjects from a trial. Our unique solutions for medical image analysis and management and iBiopsy® for imaging phenotyping, together with our global team of experts, are advancing the development of new drugs and diagnostic tools to monitor disease and assess response to therapy.

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The adjudication rates between readers in blinded independent central review (BICR) of advanced esophageal cancer trials with or without immune checkpoint initiators as first line therapy

Yan Liu [1], Yi Wang [1], Antoine Iannessi [1] - Affiliations: [1] Median Technologies, Valbonne, France

Poster presented at the ASCO Annual Meeting – June 4-6, 2022.

The objectives of this work are to document the proportion of reader discrepancies, to evaluate reader performance and to provide suggestions for the reduction of read inconsistency.

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