Scientific publications
-
03/03/2019 RECIST 1.1 evaluations in a phase II clinical trial: Does reader expertise represent a risk factor for measure reliability?
Oral presentation at the European Congress of Radiology (ECR) on Feb 27-March 3, 2019, Vienna, AustriaDownload ECR2019_presentation.pdf
Beaumont H [1], Evans T [2], Klifa C [1], Hons S [3], Chadjaa M [4], Monostori Z [5], Iannessi A [6] – Affiliations: [1] Median Technologies, Valbonne , France. [2] U. of Pennsylvania, USA. [3] Yonsei University of Medicine, Seoul, South Korea. [4] SANOFI, Vitry sur seine, France. [5] National Koranyi Institute, Budapest, Hungary. [6] Centre Antoine Lacassagne , Nice, France. -
12/14/2018 Discrepancies of assessments in a RECIST 1.1 phase II clinical trial – association between adjudication rate and variability in images and tumors selection
In imaging-based clinical trials, it is common practice to perform double reads for each image, discrepant interpretations can result from these two different evaluations. In this study we analyzed discrepancies that occurred between local investigators (LI) and blinded independent central review (BICR) by comparing reader-selected imaging scans and lesions. Our goal was to identify the causes of discrepant declarations of progressive disease (PD) between LI and BICR in a clinical trial.Read more
Beaumont H [1], Evans T [2], Klifa C [1], Guermazi A [3], Hong S [4], Chadjaa M [5], Monostori Z [6] – Affiliations: [1] Median Technologies, Valbonne, France. [2] Department of medicine, Hospital of the University of Pennsylvania, USA. [3] Quantitative Imaging Center (QIC) Boston University School of Medicine, Boston, USA. [4] Department of Radiology, Severance Hospital Yonsei University of Medicine, Seoul, South Korea. [5] Clinical Research, SANOFI, Paris, France. [6] Radiology, National Koranyi Institute of TB and pulmonology, Budapest, Hungary -
11/30/2018 High Quality Imaging in Clinical Trials – Standardization mechanisms
Presentation #18018479 at the Quantitative Imaging Reading Room, Annual Meeting of the Radiology Society of North America (RSNA) 2018; 2018 Nov. 25-29; Chicago, IL, USADownload Poster_RSNA_nov2018.pdf
Beaumont H – Affiliations: [1] Median Technologies, Valbonne, France -
11/25/2018 Can we improve cost effectiveness of oncology clinical trials workflow? A prospective RECIST 1.1 study
Poster presented at ESMO ASIA 2018, Singapore, Nov. 23 -25, 2018Download Poster_ESMO-Asia_nov2018.pdf
Hubert Beaumont [1], Antoine Iannessi [2], Catherine Klifa [1], Sebastien Patriti [2] – Affiliations: [1] Median Technologies, Valbonne, France. [2] Centre Antoine Lacassagne, Nice, France. -
11/12/2018 Feasibility of Using Deep Learning Techniques to Assess Hepatic Fibrosis Directly from Magnetic Resonance Elastography Source Images
Scientific poster presented at The Liver Meeting® 2018 | AASLD – San Francisco (Nov. 9 – Nov. 13, 2018). Study was performed in collaboration with Gilead and the University of California San Diego (UCSD)Download 20181110_AASLD2018_Poster.pdf
Marc-Michel Rohé [1], Estanislao Oubel [1], Marie-Lise Grisoni [1], Stephen Djedjos [2], Robert P. Myers [2], Hohit Loomba [3] and Michael S. Middleton [3] – Affiliations: [1] Median Technologies, Valbonne, France. [2] Gilead – [3] UCSD, San Diego, CA, USA