News & events



February 1, 2022

Discuss the 4 main causes of variability in centralized oncology radiological assessments

Inter-reader variability can create challenges in oncology trial results. During this 45-minute webinar, Median Technologies will address the 4 main causes of variability occurring during RECIST1.1 assessment and describe control strategies using data analytics and medical investigations. During this presentation, you will:

  • Discover the most common types of reader discrepancies in oncology follow-up
  • Learn how to control the causes of variability in centralized independent review and how to prevent them
  • Grasp how we at Median Technologies, handle inter-reader variability through our methods and strategies


  • Antoine Iannessi, Medical Director, Median Technologies
  • Emilie Serres, Clinical Research Scientist, Median Technologies
Register here

Previous Webinars

NOV 23, 2021

Imaging in oncology trials: can it help to make “go or no go” decisions?

This webinar is jointly organized by Labcorp Drug Development and Median Technologies. During our presentation, Labcorp and Median’s experts discuss modern imaging biomarkers covering the most important cancer hallmarks such as cell death, metabolism, vascularity, and hypoxia, and explain how they could be used in oncology trials for early response assessment and disease management.


  • Pr Laure Fournier, Academic Radiologist, AP-HP, Assistance Publique-Hôpitaux de Paris, France
  • Dr Ravi Karra, M.D, Senior Medical Director Oncology, Labcorp Drug Development
  • Dr Yan Liu, Chief Medical Officer, Median Technologies
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JULY 1, 2021

Optimizing Clinical Trial Design for Central Reads

Optimizing clinical trial design can have a huge influence on oncology studies that are dependent on imaging for evaluations. Depending on the study design, several alternatives can be considered for improving imaging results that support these endpoints: different assessment paradigms, incorporation of clinical data in addition to radiographic reads, etc… During this presentation, we review the relevance of each option for different study designs. Here are some insights that we discuss in our presentation:

  • Oncology study Endpoints include several assessments that are dependent on imaging criteria
  • When to use Ongoing Reads, Oncologist Reads and Global Reads
  • How to determine impact of read frequency including time sensitive reads during a study
  • Monitoring advantages for unique study designs and reader quality


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APRIL 13, 2021

Implementing central reviews for Response Assessment in Neuro-Oncology (RANO) criteria: what are the specificities involved?

If you are an investigator or a sponsor involved in neuro-oncology trials, this 45-minute presentation is for you: we put the focus on RANO criteria and discuss the implementation in independent centralized reviews. These criteria have a number of specificities that can be challenging, notably:

  • RANO criteria include several criteria specific to the neurological tumor and the treatment evaluated
  • Evaluation according to RANO criteria requires a strict MRI acquisition protocol which is detailed in the Image Acquisition Guidelines provided to the investigator site.
  • RANO criteria consist of composite criteria whose clinical part participates in the definition of the response to treatment and must be accessible for the centralized assessment.

Many questions arise when speaking of RANO and this presentation is a nice opportunity for you to get a detailed overview of these criteria.


  • Antoine Iannessi, Medical Director, Median Technologies
  • Jennifer Cillario, Clinical Research Scientist, Median Technologies
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FEBRUARY 18, 2021

Imaging services in clinical trials: using Business Intelligence-based reporting tools to optimize operations efficiency

Efficient reporting tools are a must have when managing the vast amount of data in clinical trials. However, reports are only meaningful when they are based on accurate operational data and challenges can arise when data is constantly changing and is integrated from multiple sources using various formats.

This 45-minute presentation provides an overview on how Business Intelligence (BI) is used at Median to develop comprehensive and meaningful reporting tools based on high quality data, for better operational efficiency. Here are some insights we will be discussing:

  • BI for data management in clinical trials, including 2 main components: data integration and data visualization,
  • BI-based data integration is the most efficient way to manage clinical data coming from multiple sources using different formats,
  • BI-based data visualization enables the aggregation of data in powerful reports, providing insights on quality monitoring, activity, forecasts, and risk management for clinical trials,
  • Implementing a BI based reporting tool is an exceedingly profitable investment for both clients and imaging CROs! Let us explain why!


  • Anne-Sophie Auroux, Head of Project Management, iCRO, Median Technologies
  • Sébastien Grosset, Chief of Operations, iCRO, Median Technologies
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